N-terminus-independent activation of c-Src via binding to a tetraspan(in) TM4SF5 in hepatocellular c...
N-terminus-independent activation of c-Src via binding to a tetraspan(in) TM4SF5 in hepatocellular carcinoma is abolished by the TM4SF5 C-terminal peptide application
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Publisher
Australia: Ivyspring International Publisher Pty Ltd
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Language
English
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Australia: Ivyspring International Publisher Pty Ltd
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Contents
Active c-Src non-receptor tyrosine kinase localizes to the plasma membrane via N-terminal lipid modification. Membranous c-Src causes cancer initiation and progression. Even though transmembrane 4 L six family member 5 (TM4SF5), a tetraspan(in), can be involved in this mechanism, the molecular and structural influence of TM4SF5 on c-Src remains unk...
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Full title
N-terminus-independent activation of c-Src via binding to a tetraspan(in) TM4SF5 in hepatocellular carcinoma is abolished by the TM4SF5 C-terminal peptide application
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8315060
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8315060
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ISSN
1838-7640
E-ISSN
1838-7640
DOI
10.7150/thno.58739