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Canonical features of human antibodies recognizing the influenza hemagglutinin trimer interface

Canonical features of human antibodies recognizing the influenza hemagglutinin trimer interface

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8321569

Canonical features of human antibodies recognizing the influenza hemagglutinin trimer interface

About this item

Full title

Canonical features of human antibodies recognizing the influenza hemagglutinin trimer interface

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2021-08, Vol.131 (15), p.1-11

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

Broadly reactive antibodies targeting the influenza A virus hemagglutinin (HA) head domain are thought to be rare and to require extensive somatic mutations or unusual structural features to achieve breadth against divergent HA subtypes. Here we describe common genetic and structural features of protective human antibodies from several individuals...

Alternative Titles

Full title

Canonical features of human antibodies recognizing the influenza hemagglutinin trimer interface

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8321569

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8321569

Other Identifiers

ISSN

1558-8238,0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI146791

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