Triglyceride-mimetic prodrugs of scutellarin enhance oral bioavailability by promoting intestinal ly...
Triglyceride-mimetic prodrugs of scutellarin enhance oral bioavailability by promoting intestinal lymphatic transport and avoiding first-pass metabolism
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Publisher
England: Taylor & Francis
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Language
English
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Publisher
England: Taylor & Francis
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Scope and Contents
Contents
The intestinal capillary pathway is the most common way to absorb oral drugs, but for drugs with poor solubility and permeability and high first-pass metabolism, this pathway is very inefficient. Although intestinal lymphatic transport of lipophilic drugs or prodrugs is a promising strategy to improve the oral delivery efficiency of these drugs. Th...
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Full title
Triglyceride-mimetic prodrugs of scutellarin enhance oral bioavailability by promoting intestinal lymphatic transport and avoiding first-pass metabolism
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8330727
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8330727
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ISSN
1071-7544
E-ISSN
1521-0464
DOI
10.1080/10717544.2021.1960928