Generation of recombinant hyperimmune globulins from diverse B-cell repertoires
Generation of recombinant hyperimmune globulins from diverse B-cell repertoires
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Author / Creator
Keating, Sheila M. , Mizrahi, Rena A. , Adams, Matthew S. , Asensio, Michael A. , Benzie, Emily , Carter, Kyle P. , Chiang, Yao , Edgar, Robert C. , Gautam, Bishal K. , Gras, Ashley , Leong, Jackson , Leong, Renee , Lim, Yoong Wearn , Manickam, Vishal A. , Medina-Cucurella, Angelica V. , Niedecken, Ariel R. , Saini, Jasmeen , Simons, Jan Fredrik , Spindler, Matthew J. , Stadtmiller, Kacy , Tinsley, Brendan , Wagner, Ellen K. , Wayham, Nicholas , Tracy, LaRee , Lundberg, Carina Vingsbo , Büscher, Dirk , Terencio, Jose Vicente , Roalfe, Lucy , Pearce, Emma , Richardson, Hayley , Goldblatt, David , Ramjag, Anushka T. , Carrington, Christine V. F. , Simmons, Graham , Muench, Marcus O. , Chamow, Steven M. , Monroe, Bryan , Olson, Charles , Oguin, Thomas H. , Lynch, Heather , Jeanfreau, Robert , Mosher, Rachel A. , Walch, Matthew J. , Bartley, Christopher R. , Ross, Carl A. , Meyer, Everett H. , Adler, Adam S. and Johnson, David S.
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Plasma-derived polyclonal antibody therapeutics, such as intravenous immunoglobulin, have multiple drawbacks, including low potency, impurities, insufficient supply and batch-to-batch variation. Here we describe a microfluidics and molecular genomics strategy for capturing diverse mammalian antibody repertoires to create recombinant multivalent hyp...
Alternative Titles
Full title
Generation of recombinant hyperimmune globulins from diverse B-cell repertoires
Authors, Artists and Contributors
Author / Creator
Mizrahi, Rena A.
Adams, Matthew S.
Asensio, Michael A.
Benzie, Emily
Carter, Kyle P.
Chiang, Yao
Edgar, Robert C.
Gautam, Bishal K.
Gras, Ashley
Leong, Jackson
Leong, Renee
Lim, Yoong Wearn
Manickam, Vishal A.
Medina-Cucurella, Angelica V.
Niedecken, Ariel R.
Saini, Jasmeen
Simons, Jan Fredrik
Spindler, Matthew J.
Stadtmiller, Kacy
Tinsley, Brendan
Wagner, Ellen K.
Wayham, Nicholas
Tracy, LaRee
Lundberg, Carina Vingsbo
Büscher, Dirk
Terencio, Jose Vicente
Roalfe, Lucy
Pearce, Emma
Richardson, Hayley
Goldblatt, David
Ramjag, Anushka T.
Carrington, Christine V. F.
Simmons, Graham
Muench, Marcus O.
Chamow, Steven M.
Monroe, Bryan
Olson, Charles
Oguin, Thomas H.
Lynch, Heather
Jeanfreau, Robert
Mosher, Rachel A.
Walch, Matthew J.
Bartley, Christopher R.
Ross, Carl A.
Meyer, Everett H.
Adler, Adam S.
Johnson, David S.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8355030
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8355030
Other Identifiers
ISSN
1087-0156,1546-1696
E-ISSN
1546-1696
DOI
10.1038/s41587-021-00894-8
