Iterative single-cell multi-omic integration using online learning
Iterative single-cell multi-omic integration using online learning
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
Integrating large single-cell gene expression, chromatin accessibility and DNA methylation datasets requires general and scalable computational approaches. Here we describe online integrative non-negative matrix factorization (iNMF), an algorithm for integrating large, diverse and continually arriving single-cell datasets. Our approach scales to ar...
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Full title
Iterative single-cell multi-omic integration using online learning
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8355612
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8355612
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ISSN
1087-0156
E-ISSN
1546-1696
DOI
10.1038/s41587-021-00867-x