Targeting cancer stem cells in medulloblastoma by inhibiting AMBRA1 dual function in autophagy and S...
Targeting cancer stem cells in medulloblastoma by inhibiting AMBRA1 dual function in autophagy and STAT3 signalling
About this item
Full title
Author / Creator
Nazio, Francesca , Po, Agnese , Abballe, Luana , Ballabio, Claudio , Diomedi Camassei, Francesca , Bordi, Matteo , Camera, Antonio , Caruso, Simona , Caruana, Ignazio , Pezzullo, Marco , Ferraina, Caterina , Milletti, Giacomo , Gianesello, Matteo , Reddel, Sofia , De Luca, Carmen Dolores , Ceglie, Donatella , Marinelli, Sara , Campello, Silvia , Papaleo, Elena , Miele, Evelina , Cacchione, Antonella , Carai, Andrea , Vinci, Maria , Velardi, Enrico , De Angelis, Biagio , Tiberi, Luca , Quintarelli, Concetta , Mastronuzzi, Angela , Ferretti, Elisabetta , Locatelli, Franco and Cecconi, Francesco
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
Formats
Publication information
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Subjects
More information
Scope and Contents
Contents
Medulloblastoma (MB) is a childhood malignant brain tumour comprising four main subgroups characterized by different genetic alterations and rate of mortality. Among MB subgroups, patients with enhanced levels of the c-MYC oncogene (MB
Group3
) have the poorest prognosis. Here we identify a previously unrecognized role of the pro-autophagy fa...
Alternative Titles
Full title
Targeting cancer stem cells in medulloblastoma by inhibiting AMBRA1 dual function in autophagy and STAT3 signalling
Authors, Artists and Contributors
Author / Creator
Po, Agnese
Abballe, Luana
Ballabio, Claudio
Diomedi Camassei, Francesca
Bordi, Matteo
Camera, Antonio
Caruso, Simona
Caruana, Ignazio
Pezzullo, Marco
Ferraina, Caterina
Milletti, Giacomo
Gianesello, Matteo
Reddel, Sofia
De Luca, Carmen Dolores
Ceglie, Donatella
Marinelli, Sara
Campello, Silvia
Papaleo, Elena
Miele, Evelina
Cacchione, Antonella
Carai, Andrea
Vinci, Maria
Velardi, Enrico
De Angelis, Biagio
Tiberi, Luca
Quintarelli, Concetta
Mastronuzzi, Angela
Ferretti, Elisabetta
Locatelli, Franco
Cecconi, Francesco
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8357694
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8357694
Other Identifiers
ISSN
0001-6322
E-ISSN
1432-0533
DOI
10.1007/s00401-021-02347-7
