The impact of hepatic and renal function on panitumumab exposures in patients with metastatic RAS wi...
The impact of hepatic and renal function on panitumumab exposures in patients with metastatic RAS wild-type colorectal cancer
About this item
Full title
Author / Creator
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
Formats
Publication information
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Subjects
More information
Scope and Contents
Contents
Purpose
Panitumumab is a human monoclonal antibody targeting the epidermal growth factor receptor for the treatment of wild-type
RAS
metastatic colorectal cancer (mCRC). Currently, no dedicated clinical studies have evaluated the effect of organ impairment on the pharmacokinetics of panitumumab. Here, we present data from late phase studie...
Alternative Titles
Full title
The impact of hepatic and renal function on panitumumab exposures in patients with metastatic RAS wild-type colorectal cancer
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8367910
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8367910
Other Identifiers
ISSN
0344-5704
E-ISSN
1432-0843
DOI
10.1007/s00280-021-04319-w
