The E3 ligase Itch is a negative regulator of the homeostasis and function of hematopoietic stem cel...
The E3 ligase Itch is a negative regulator of the homeostasis and function of hematopoietic stem cells
About this item
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Publisher
New York: Nature Publishing Group US
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Language
English
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New York: Nature Publishing Group US
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Contents
The molecular machinery that regulates the self-renewal of hematopoietic stem cells remains elusive. Flavell and co-workers show that the type E3 ubiquitin ligase Itch negatively regulates the development and function of these cells.
Although hematopoietic stem cells (HSCs) are the most thoroughly characterized type of adult stem cell, the intri...
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Full title
The E3 ligase Itch is a negative regulator of the homeostasis and function of hematopoietic stem cells
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8369725
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8369725
Other Identifiers
ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/ni.2021
