Development of an Ewing sarcoma cell line with resistance to EWS‑FLI1 inhibitor YK‑4‑279
Development of an Ewing sarcoma cell line with resistance to EWS‑FLI1 inhibitor YK‑4‑279
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Author / Creator
Publisher
Greece: Spandidos Publications
Journal title
Language
English
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Publisher
Greece: Spandidos Publications
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Scope and Contents
Contents
Despite Ewing sarcoma (ES) being the second most common pediatric malignancy of bone and soft tissue, few novel therapeutic approaches have been introduced over the past few decades. ES contains a pathognomonic chromosomal translocation that leads to a fusion protein between EWSR1 and an ets family member, most often FLI1. EWS‑FLI1 is the most comm...
Alternative Titles
Full title
Development of an Ewing sarcoma cell line with resistance to EWS‑FLI1 inhibitor YK‑4‑279
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8371434
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8371434
Other Identifiers
ISSN
1791-2997,1791-3004
E-ISSN
1791-3004
DOI
10.3892/mmr.2020.10948
