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Targeting B cell receptor signaling with ibrutinib in diffuse large B cell lymphoma

Targeting B cell receptor signaling with ibrutinib in diffuse large B cell lymphoma

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8372245

Targeting B cell receptor signaling with ibrutinib in diffuse large B cell lymphoma

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Clinical testing of BCR inhibition on DLBCL reveals determinants of response.
The two major subtypes of diffuse large B cell lymphoma (DLBCL)—activated B cell–like (ABC) and germinal center B cell–like (GCB)—arise by distinct mechanisms, with ABC selectively acquiring mutations that target the B cell receptor (BCR), fostering chronic active BCR...

Alternative Titles

Full title

Targeting B cell receptor signaling with ibrutinib in diffuse large B cell lymphoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8372245

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8372245

Other Identifiers

ISSN

1078-8956

E-ISSN

1546-170X

DOI

10.1038/nm.3884

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