SLC15A4 mediates M1-prone metabolic shifts in macrophages and guards immune cells from metabolic str...
SLC15A4 mediates M1-prone metabolic shifts in macrophages and guards immune cells from metabolic stress
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Author / Creator
Kobayashi, Toshihiko , Nguyen-Tien, Dat , Sorimachi, Yuriko , Sugiura, Yuki , Suzuki, Takehiro , Karyu, Hitomi , Shimabukuro-Demoto, Shiho , Uemura, Tatsuki , Okamura, Tadashi , Taguchi, Tomohiko , Ueki, Kohjiro , Kato, Norihiro , Goda, Nobuhito , Dohmae, Naoshi , Takubo, Keiyo , Suematsu, Makoto and Toyama-Sorimachi, Noriko
Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
The amino acid and oligopeptide transporter Solute carrier family 15 member A4 (SLC15A4), which resides in lysosomes and is preferentially expressed in immune cells, plays critical roles in the pathogenesis of lupus and colitis in murine models. Toll-like receptor (TLR) 7/9- and nucleotide-binding oligomerization domain-containing protein 1 (NOD1)-...
Alternative Titles
Full title
SLC15A4 mediates M1-prone metabolic shifts in macrophages and guards immune cells from metabolic stress
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8379930
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8379930
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.2100295118
