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Novel allosteric ligands of the angiotensin receptor AT1R as autoantibody blockers

Novel allosteric ligands of the angiotensin receptor AT1R as autoantibody blockers

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8379978

Novel allosteric ligands of the angiotensin receptor AT1R as autoantibody blockers

About this item

Full title

Novel allosteric ligands of the angiotensin receptor AT1R as autoantibody blockers

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2021-08, Vol.118 (33), p.1-10

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

While orthosteric ligands of the angiotensin II (AngII) type 1 receptor (AT1R) are available for clinical and research applications, allosteric ligands are not known for this important G protein-coupled receptor (GPCR). Allosteric ligands are useful tools to modulate receptor pharmacology and subtype selectivity. Here, we report AT1R allosteric lig...

Alternative Titles

Full title

Novel allosteric ligands of the angiotensin receptor AT1R as autoantibody blockers

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8379978

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8379978

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.2019126118

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