Novel allosteric ligands of the angiotensin receptor AT1R as autoantibody blockers
Novel allosteric ligands of the angiotensin receptor AT1R as autoantibody blockers
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Contents
While orthosteric ligands of the angiotensin II (AngII) type 1 receptor (AT1R) are available for clinical and research applications, allosteric ligands are not known for this important G protein-coupled receptor (GPCR). Allosteric ligands are useful tools to modulate receptor pharmacology and subtype selectivity. Here, we report AT1R allosteric lig...
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Full title
Novel allosteric ligands of the angiotensin receptor AT1R as autoantibody blockers
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8379978
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8379978
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.2019126118