A human-airway-on-a-chip for the rapid identification of candidate antiviral therapeutics and prophy...
A human-airway-on-a-chip for the rapid identification of candidate antiviral therapeutics and prophylactics
About this item
Full title
Author / Creator
Si, Longlong , Bai, Haiqing , Rodas, Melissa , Cao, Wuji , Oh, Crystal Yuri , Jiang, Amanda , Moller, Rasmus , Hoagland, Daisy , Oishi, Kohei , Horiuchi, Shu , Uhl, Skyler , Blanco-Melo, Daniel , Albrecht, Randy A. , Liu, Wen-Chun , Jordan, Tristan , Nilsson-Payant, Benjamin E. , Golynker, Ilona , Frere, Justin , Logue, James , Haupt, Robert , McGrath, Marisa , Weston, Stuart , Zhang, Tian , Plebani, Roberto , Soong, Mercy , Nurani, Atiq , Kim, Seong Min , Zhu, Danni Y. , Benam, Kambez H. , Goyal, Girija , Gilpin, Sarah E. , Prantil-Baun, Rachelle , Gygi, Steven P. , Powers, Rani K. , Carlson, Kenneth E. , Frieman, Matthew , tenOever, Benjamin R. and Ingber, Donald E.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
The rapid repurposing of antivirals is particularly pressing during pandemics. However, rapid assays for assessing candidate drugs typically involve in vitro screens and cell lines that do not recapitulate human physiology at the tissue and organ levels. Here we show that a microfluidic bronchial-airway-on-a-chip lined by highly differentiated huma...
Alternative Titles
Full title
A human-airway-on-a-chip for the rapid identification of candidate antiviral therapeutics and prophylactics
Authors, Artists and Contributors
Author / Creator
Bai, Haiqing
Rodas, Melissa
Cao, Wuji
Oh, Crystal Yuri
Jiang, Amanda
Moller, Rasmus
Hoagland, Daisy
Oishi, Kohei
Horiuchi, Shu
Uhl, Skyler
Blanco-Melo, Daniel
Albrecht, Randy A.
Liu, Wen-Chun
Jordan, Tristan
Nilsson-Payant, Benjamin E.
Golynker, Ilona
Frere, Justin
Logue, James
Haupt, Robert
McGrath, Marisa
Weston, Stuart
Zhang, Tian
Plebani, Roberto
Soong, Mercy
Nurani, Atiq
Kim, Seong Min
Zhu, Danni Y.
Benam, Kambez H.
Goyal, Girija
Gilpin, Sarah E.
Prantil-Baun, Rachelle
Gygi, Steven P.
Powers, Rani K.
Carlson, Kenneth E.
Frieman, Matthew
tenOever, Benjamin R.
Ingber, Donald E.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8387338
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8387338
Other Identifiers
ISSN
2157-846X
E-ISSN
2157-846X
DOI
10.1038/s41551-021-00718-9
