The Unfolded Protein Response Is a Major Driver of LCN2 Expression in BCR–ABL- and JAK2V617F-Positiv...
The Unfolded Protein Response Is a Major Driver of LCN2 Expression in BCR–ABL- and JAK2V617F-Positive MPN
About this item
Full title
Author / Creator
Tillmann, Stefan , Olschok, Kathrin , Schröder, Sarah K. , Bütow, Marlena , Baumeister, Julian , Kalmer, Milena , Preußger, Vera , Weinbergerova, Barbora , Kricheldorf, Kim , Mayer, Jiri , Kubesova, Blanka , Racil, Zdenek , Wessiepe, Martina , Eschweiler, Jörg , Isfort, Susanne , Brümmendorf, Tim H. , Becker, Walter , Schemionek, Mirle , Weiskirchen, Ralf , Koschmieder, Steffen and Chatain, Nicolas
Publisher
Basel: MDPI AG
Journal title
Language
English
Formats
Publication information
Publisher
Basel: MDPI AG
Subjects
More information
Scope and Contents
Contents
Lipocalin 2 (LCN2), a proinflammatory mediator, is involved in the pathogenesis of myeloproliferative neoplasms (MPN). Here, we investigated the molecular mechanisms of LCN2 overexpression in MPN. LCN2 mRNA expression was 20-fold upregulated in peripheral blood (PB) mononuclear cells of chronic myeloid leukemia (CML) and myelofibrosis (MF) patients...
Alternative Titles
Full title
The Unfolded Protein Response Is a Major Driver of LCN2 Expression in BCR–ABL- and JAK2V617F-Positive MPN
Authors, Artists and Contributors
Author / Creator
Olschok, Kathrin
Schröder, Sarah K.
Bütow, Marlena
Baumeister, Julian
Kalmer, Milena
Preußger, Vera
Weinbergerova, Barbora
Kricheldorf, Kim
Mayer, Jiri
Kubesova, Blanka
Racil, Zdenek
Wessiepe, Martina
Eschweiler, Jörg
Isfort, Susanne
Brümmendorf, Tim H.
Becker, Walter
Schemionek, Mirle
Weiskirchen, Ralf
Koschmieder, Steffen
Chatain, Nicolas
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8391615
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8391615
Other Identifiers
ISSN
2072-6694
E-ISSN
2072-6694
DOI
10.3390/cancers13164210
