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Endothelial FGF signaling is protective in hypoxia-induced pulmonary hypertension

Endothelial FGF signaling is protective in hypoxia-induced pulmonary hypertension

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8409583

Endothelial FGF signaling is protective in hypoxia-induced pulmonary hypertension

About this item

Full title

Endothelial FGF signaling is protective in hypoxia-induced pulmonary hypertension

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2021-09, Vol.131 (17), p.1-17

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

Hypoxia-induced pulmonary hypertension (PH) is one of the most common and deadliest forms of PH. Fibroblast growth factor receptors 1 and 2 (FGFR1/2) are elevated in patients with PH and in mice exposed to chronic hypoxia. Endothelial FGFR1/2 signaling is important for the adaptive response to several injury types and we hypothesized that endotheli...

Alternative Titles

Full title

Endothelial FGF signaling is protective in hypoxia-induced pulmonary hypertension

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8409583

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8409583

Other Identifiers

ISSN

1558-8238,0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI141467

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