Endothelial FGF signaling is protective in hypoxia-induced pulmonary hypertension
Endothelial FGF signaling is protective in hypoxia-induced pulmonary hypertension
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United States: American Society for Clinical Investigation
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English
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United States: American Society for Clinical Investigation
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Hypoxia-induced pulmonary hypertension (PH) is one of the most common and deadliest forms of PH. Fibroblast growth factor receptors 1 and 2 (FGFR1/2) are elevated in patients with PH and in mice exposed to chronic hypoxia. Endothelial FGFR1/2 signaling is important for the adaptive response to several injury types and we hypothesized that endotheli...
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Endothelial FGF signaling is protective in hypoxia-induced pulmonary hypertension
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8409583
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8409583
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ISSN
1558-8238,0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI141467