Dactinomycin induces complete remission associated with nucleolar stress response in relapsed/refrac...
Dactinomycin induces complete remission associated with nucleolar stress response in relapsed/refractory NPM1-mutated AML
About this item
Full title
Author / Creator
Gionfriddo, Ilaria , Brunetti, Lorenzo , Mezzasoma, Federica , Milano, Francesca , Cardinali, Valeria , Ranieri, Roberta , Venanzi, Alessandra , Pierangeli, Sara , Vetro, Calogero , Spinozzi, Giulio , Dorillo, Erica , Wu, Hsin Chieh , Berthier, Caroline , Ciurnelli, Raffaella , Griffin, Melanie J. , Jennings, Claire E. , Tiacci, Enrico , Sportoletti, Paolo , Falzetti, Franca , de Thé, Hugues , Veal, Gareth J. , Martelli, Maria Paola and Falini, Brunangelo
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Acute myeloid leukemia (AML) with mutated
NPM1
accounts for one-third of newly diagnosed AML. Despite recent advances, treatment of relapsed/refractory
NPM1
-mutated AML remains challenging, with the majority of patients eventually dying due to disease progression. Moreover, the prognosis is particularly poor in elderly and unfit patien...
Alternative Titles
Full title
Dactinomycin induces complete remission associated with nucleolar stress response in relapsed/refractory NPM1-mutated AML
Authors, Artists and Contributors
Author / Creator
Brunetti, Lorenzo
Mezzasoma, Federica
Milano, Francesca
Cardinali, Valeria
Ranieri, Roberta
Venanzi, Alessandra
Pierangeli, Sara
Vetro, Calogero
Spinozzi, Giulio
Dorillo, Erica
Wu, Hsin Chieh
Berthier, Caroline
Ciurnelli, Raffaella
Griffin, Melanie J.
Jennings, Claire E.
Tiacci, Enrico
Sportoletti, Paolo
Falzetti, Franca
de Thé, Hugues
Veal, Gareth J.
Martelli, Maria Paola
Falini, Brunangelo
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8410589
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8410589
Other Identifiers
ISSN
0887-6924
E-ISSN
1476-5551
DOI
10.1038/s41375-021-01192-7
