Effect of severe renal impairment on the pharmacokinetics of brigatinib
Effect of severe renal impairment on the pharmacokinetics of brigatinib
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Publisher
New York: Springer US
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Language
English
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Publisher
New York: Springer US
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Summary
Background
Brigatinib, a next-generation anaplastic lymphoma kinase (ALK) inhibitor, targets activated, mutant forms of ALK and overcomes mechanisms of resistance to the ALK inhibitors crizotinib, ceritinib, and alectinib. Brigatinib is approved in multiple countries for treatment of patients with ALK-positive non–small cell lung canc...
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Full title
Effect of severe renal impairment on the pharmacokinetics of brigatinib
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8426299
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8426299
Other Identifiers
ISSN
0167-6997
E-ISSN
1573-0646
DOI
10.1007/s10637-021-01095-5