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Metformin Attenuates Postinfarction Myocardial Fibrosis and Inflammation in Mice

Metformin Attenuates Postinfarction Myocardial Fibrosis and Inflammation in Mice

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8430638

Metformin Attenuates Postinfarction Myocardial Fibrosis and Inflammation in Mice

About this item

Full title

Metformin Attenuates Postinfarction Myocardial Fibrosis and Inflammation in Mice

Publisher

Basel: MDPI AG

Journal title

International journal of molecular sciences, 2021-09, Vol.22 (17), p.9393

Language

English

Formats

Publication information

Publisher

Basel: MDPI AG

More information

Scope and Contents

Contents

Diabetes is a major risk factor for the development of cardiovascular disease with a higher incidence of myocardial infarction. This study explores the role of metformin, a first-line antihyperglycemic agent, in postinfarction fibrotic and inflammatory remodeling in mice. Three-month-old C57BI/6J mice were submitted to 30 min cardiac ischemia follo...

Alternative Titles

Full title

Metformin Attenuates Postinfarction Myocardial Fibrosis and Inflammation in Mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8430638

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8430638

Other Identifiers

ISSN

1422-0067,1661-6596

E-ISSN

1422-0067

DOI

10.3390/ijms22179393

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