Quantitative Analysis of the Potency of Equimolar Two-Drug Combinations and Combi-Molecules Involvin...
Quantitative Analysis of the Potency of Equimolar Two-Drug Combinations and Combi-Molecules Involving Kinase Inhibitors In Vitro: The Concept of Balanced Targeting
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Basel: MDPI AG
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English
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Basel: MDPI AG
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The median-effect principle proposed by Chou and Talalay is the most effective approach to parameterize interactions between several agents in combination. However, this method cannot be used to evaluate the effectiveness of equimolar drug combinations, which are comparative references for dual-targeting molecular design. Here, using data acquired...
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Full title
Quantitative Analysis of the Potency of Equimolar Two-Drug Combinations and Combi-Molecules Involving Kinase Inhibitors In Vitro: The Concept of Balanced Targeting
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8430702
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8430702
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ISSN
1422-0067,1661-6596
E-ISSN
1422-0067,1661-6596
DOI
10.3390/ijms22179569
