High linear energy transfer carbon-ion irradiation upregulates PD-L1 expression more significantly t...
High linear energy transfer carbon-ion irradiation upregulates PD-L1 expression more significantly than X-rays in human osteosarcoma U2OS cells
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Author / Creator
Permata, Tiara Bunga Mayang , Sato, Hiro , Gu, Wenchao , Kakoti, Sangeeta , Uchihara, Yuki , Yoshimatsu, Yukihiko , Sato, Itaru , Kato, Reona , Yamauchi, Motohiro , Suzuki, Keiji , Oike, Takahiro , Tsushima, Yoshito , Gondhowiardjo, Soehartati , Ohno, Tatsuya , Yasuhara, Takaaki and Shibata, Atsushi
Publisher
England: Oxford University Press
Journal title
Language
English
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Publisher
England: Oxford University Press
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Scope and Contents
Contents
Programmed death ligand 1 (PD-L1) expression on the surface of cancer cells affects the efficacy of anti-PD-1/PD-L1 immune checkpoint therapy. However, the mechanism underlying PD-L1 expression in cancer cells is not fully understood, particularly after ionizing radiation (IR). Here, we examined the impact of high linear energy transfer (LET) carbo...
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Full title
High linear energy transfer carbon-ion irradiation upregulates PD-L1 expression more significantly than X-rays in human osteosarcoma U2OS cells
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8438258
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8438258
Other Identifiers
ISSN
0449-3060
E-ISSN
1349-9157
DOI
10.1093/jrr/rrab050