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Natural killer cell immunosuppressive function requires CXCR3-dependent redistribution within lympho...

Natural killer cell immunosuppressive function requires CXCR3-dependent redistribution within lympho...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8439606

Natural killer cell immunosuppressive function requires CXCR3-dependent redistribution within lymphoid tissues

About this item

Full title

Natural killer cell immunosuppressive function requires CXCR3-dependent redistribution within lymphoid tissues

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2021-09, Vol.131 (18)

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

NK cell suppression of T cells is a key determinant of viral pathogenesis and vaccine efficacy. This process involves perforin-dependent elimination of activated CD4+ T cells during the first 3 days of infection. Although this mechanism requires cell-cell contact, NK cells and T cells typically reside in different compartments of lymphoid tissues a...

Alternative Titles

Full title

Natural killer cell immunosuppressive function requires CXCR3-dependent redistribution within lymphoid tissues

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8439606

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8439606

Other Identifiers

ISSN

1558-8238,0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI146686

How to access this item