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Systematic evaluation of chromosome conformation capture assays

Systematic evaluation of chromosome conformation capture assays

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8446342

Systematic evaluation of chromosome conformation capture assays

About this item

Full title

Systematic evaluation of chromosome conformation capture assays

Publisher

New York: Nature Publishing Group US

Journal title

Nature methods, 2021-09, Vol.18 (9), p.1046-1055

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Chromosome conformation capture (3C) assays are used to map chromatin interactions genome-wide. Chromatin interaction maps provide insights into the spatial organization of chromosomes and the mechanisms by which they fold. Hi-C and Micro-C are widely used 3C protocols that differ in key experimental parameters including cross-linking chemistry and...

Alternative Titles

Full title

Systematic evaluation of chromosome conformation capture assays

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8446342

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8446342

Other Identifiers

ISSN

1548-7091,1548-7105

E-ISSN

1548-7105

DOI

10.1038/s41592-021-01248-7

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