Characteristics of anti-CD19 CAR T cell infusion products associated with efficacy and toxicity in p...
Characteristics of anti-CD19 CAR T cell infusion products associated with efficacy and toxicity in patients with large B cell lymphomas
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Author / Creator
Deng, Qing , Han, Guangchun , Puebla-Osorio, Nahum , Ma, Man Chun John , Strati, Paolo , Chasen, Beth , Dai, Enyu , Dang, Minghao , Jain, Neeraj , Yang, Haopeng , Wang, Yuanxin , Zhang, Shaojun , Wang, Ruiping , Chen, Runzhe , Showell, Jordan , Ghosh, Sreejoyee , Patchva, Sridevi , Zhang, Qi , Sun, Ryan , Hagemeister, Frederick , Fayad, Luis , Samaniego, Felipe , Lee, Hans C. , Nastoupil, Loretta J. , Fowler, Nathan , Eric Davis, R. , Westin, Jason , Neelapu, Sattva S. , Wang, Linghua and Green, Michael R.
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Autologous chimeric antigen receptor (CAR) T cell therapies targeting CD19 have high efficacy in large B cell lymphomas (LBCLs), but long-term remissions are observed in less than half of patients, and treatment-associated adverse events, such as immune effector cell-associated neurotoxicity syndrome (ICANS), are a clinical challenge. We performed...
Alternative Titles
Full title
Characteristics of anti-CD19 CAR T cell infusion products associated with efficacy and toxicity in patients with large B cell lymphomas
Authors, Artists and Contributors
Author / Creator
Han, Guangchun
Puebla-Osorio, Nahum
Ma, Man Chun John
Strati, Paolo
Chasen, Beth
Dai, Enyu
Dang, Minghao
Jain, Neeraj
Yang, Haopeng
Wang, Yuanxin
Zhang, Shaojun
Wang, Ruiping
Chen, Runzhe
Showell, Jordan
Ghosh, Sreejoyee
Patchva, Sridevi
Zhang, Qi
Sun, Ryan
Hagemeister, Frederick
Fayad, Luis
Samaniego, Felipe
Lee, Hans C.
Nastoupil, Loretta J.
Fowler, Nathan
Eric Davis, R.
Westin, Jason
Neelapu, Sattva S.
Wang, Linghua
Green, Michael R.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8446909
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8446909
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/s41591-020-1061-7