Advancing targeted protein degradation for cancer therapy
Advancing targeted protein degradation for cancer therapy
About this item
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Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
The human proteome contains approximately 20,000 proteins, and it is estimated that more than 600 of them are functionally important for various types of cancers, including nearly 400 non-enzyme proteins that are challenging to target by traditional occupancy-driven pharmacology. Recent advances in the development of small-molecule degraders, inclu...
Alternative Titles
Full title
Advancing targeted protein degradation for cancer therapy
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8463487
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8463487
Other Identifiers
ISSN
1474-175X,1474-1768
E-ISSN
1474-1768
DOI
10.1038/s41568-021-00365-x
