Robustness of Phylogenetic Inference to Model Misspecification Caused by Pairwise Epistasis
Robustness of Phylogenetic Inference to Model Misspecification Caused by Pairwise Epistasis
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United States: Oxford University Press
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English
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United States: Oxford University Press
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Likelihood-based phylogenetic inference posits a probabilistic model of character state change along branches of a phylogenetic tree. These models typically assume statistical independence of sites in the sequence alignment. This is a restrictive assumption that facilitates computational tractability, but ignores how epistasis, the effect of geneti...
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Robustness of Phylogenetic Inference to Model Misspecification Caused by Pairwise Epistasis
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8476159
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8476159
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ISSN
1537-1719,0737-4038
E-ISSN
1537-1719
DOI
10.1093/molbev/msab163