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Robustness of Phylogenetic Inference to Model Misspecification Caused by Pairwise Epistasis

Robustness of Phylogenetic Inference to Model Misspecification Caused by Pairwise Epistasis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8476159

Robustness of Phylogenetic Inference to Model Misspecification Caused by Pairwise Epistasis

About this item

Full title

Robustness of Phylogenetic Inference to Model Misspecification Caused by Pairwise Epistasis

Publisher

United States: Oxford University Press

Journal title

Molecular biology and evolution, 2021-10, Vol.38 (10), p.4603-4615

Language

English

Formats

Publication information

Publisher

United States: Oxford University Press

More information

Scope and Contents

Contents

Likelihood-based phylogenetic inference posits a probabilistic model of character state change along branches of a phylogenetic tree. These models typically assume statistical independence of sites in the sequence alignment. This is a restrictive assumption that facilitates computational tractability, but ignores how epistasis, the effect of geneti...

Alternative Titles

Full title

Robustness of Phylogenetic Inference to Model Misspecification Caused by Pairwise Epistasis

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8476159

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8476159

Other Identifiers

ISSN

1537-1719,0737-4038

E-ISSN

1537-1719

DOI

10.1093/molbev/msab163

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