Broadly neutralizing antibody–derived CAR T cells reduce viral reservoir in individuals infected wit...
Broadly neutralizing antibody–derived CAR T cells reduce viral reservoir in individuals infected with HIV-1
About this item
Full title
Author / Creator
Liu, Bingfeng , Zhang, Wanying , Xia, Baijin , Jing, Shuliang , Du, Yingying , Zou, Fan , Li, Rong , Lu, Lijuan , Chen, Shaozhen , Li, Yonghong , Hu, Qifei , Lin, Yingtong , Zhang, Yiwen , He, Zhangping , Zhang, Xu , Chen, Xiejie , Peng, Tao , Tang, Xiaoping , Cai, Weiping , Pan, Ting , Li, Linghua and Zhang, Hui
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for Clinical Investigation
Subjects
More information
Scope and Contents
Contents
BACKGROUNDChimeric antigen receptor (CAR) T cells have emerged as an approach to treat malignant tumors. This strategy has also been proposed for the treatment of HIV-1 infection. We have developed a broadly neutralizing antibody-derived (bNAb-derived) CAR T cell therapy that can exert specific cytotoxic activity against HIV-1-infected cells.METHOD...
Alternative Titles
Full title
Broadly neutralizing antibody–derived CAR T cells reduce viral reservoir in individuals infected with HIV-1
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8483761
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8483761
Other Identifiers
ISSN
1558-8238,0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI150211
