Therapeutically reprogrammed nutrient signalling enhances nanoparticulate albumin bound drug uptake...
Therapeutically reprogrammed nutrient signalling enhances nanoparticulate albumin bound drug uptake and efficacy in KRAS-mutant cancer
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Nanoparticulate albumin bound paclitaxel (nab-paclitaxel, nab-PTX) is among the most widely prescribed nanomedicines in clinical use, yet it remains unclear how nanoformulation affects nab-PTX behaviour in the tumour microenvironment. Here, we quantified the biodistribution of the albumin carrier and its chemotherapeutic payload in optically cleare...
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Therapeutically reprogrammed nutrient signalling enhances nanoparticulate albumin bound drug uptake and efficacy in KRAS-mutant cancer
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8491539
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8491539
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ISSN
1748-3387
E-ISSN
1748-3395
DOI
10.1038/s41565-021-00897-1
