Single-cell epigenomics reveals mechanisms of human cortical development
Single-cell epigenomics reveals mechanisms of human cortical development
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Author / Creator
Ziffra, Ryan S. , Kim, Chang N. , Ross, Jayden M. , Wilfert, Amy , Turner, Tychele N. , Haeussler, Maximilian , Casella, Alex M. , Przytycki, Pawel F. , Keough, Kathleen C. , Shin, David , Bogdanoff, Derek , Kreimer, Anat , Pollard, Katherine S. , Ament, Seth A. , Eichler, Evan E. , Ahituv, Nadav and Nowakowski, Tomasz J.
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
During mammalian development, differences in chromatin state coincide with cellular differentiation and reflect changes in the gene regulatory landscape
1
. In the developing brain, cell fate specification and topographic identity are important for defining cell identity
2
and confer selective vulnerabilities to neurodevelopmental disor...
Alternative Titles
Full title
Single-cell epigenomics reveals mechanisms of human cortical development
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8494642
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8494642
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-021-03209-8
