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Shikonin protects against lipopolysaccharide‐induced inflammation and apoptosis in human nucleus pul...

Shikonin protects against lipopolysaccharide‐induced inflammation and apoptosis in human nucleus pul...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8497831

Shikonin protects against lipopolysaccharide‐induced inflammation and apoptosis in human nucleus pulposus cells through the nuclear factor‐kappa B pathway

About this item

Full title

Shikonin protects against lipopolysaccharide‐induced inflammation and apoptosis in human nucleus pulposus cells through the nuclear factor‐kappa B pathway

Publisher

United States: John Wiley & Sons, Inc

Journal title

Food science & nutrition, 2021-10, Vol.9 (10), p.5583-5589

Language

English

Formats

Publication information

Publisher

United States: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

Objective
To investigate the protective effect and mechanism of shikonin on human intervertebral disk degeneration.
Methods
Human primary nucleus pulposus (NP) cells cultured in vitro were used for the experiments. The effects of different concentrations of shikonin (1, 2, 4, 8, and 16 µM) on the activity of lipopolysaccharide (LPS)‐induce...

Alternative Titles

Full title

Shikonin protects against lipopolysaccharide‐induced inflammation and apoptosis in human nucleus pulposus cells through the nuclear factor‐kappa B pathway

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8497831

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8497831

Other Identifiers

ISSN

2048-7177

E-ISSN

2048-7177

DOI

10.1002/fsn3.2519

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