Human cerebral organoids establish subcortical projections in the mouse brain after transplantation
Human cerebral organoids establish subcortical projections in the mouse brain after transplantation
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Author / Creator
Dong, Xin , Xu, Shi-Bo , Chen, Xin , Tao, Mengdan , Tang, Xiao-Yan , Fang, Kai-Heng , Xu, Min , Pan, Yufeng , Chen, Yuejun , He, Shuijin and Liu, Yan
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Numerous studies have used human pluripotent stem cell-derived cerebral organoids to elucidate the mystery of human brain development and model neurological diseases in vitro, but the potential for grafted organoid-based therapy in vivo remains unknown. Here, we optimized a culturing protocol capable of efficiently generating small human cerebral o...
Alternative Titles
Full title
Human cerebral organoids establish subcortical projections in the mouse brain after transplantation
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8505255
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8505255
Other Identifiers
ISSN
1359-4184
E-ISSN
1476-5578
DOI
10.1038/s41380-020-00910-4