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Human cerebral organoids establish subcortical projections in the mouse brain after transplantation

Human cerebral organoids establish subcortical projections in the mouse brain after transplantation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8505255

Human cerebral organoids establish subcortical projections in the mouse brain after transplantation

About this item

Full title

Human cerebral organoids establish subcortical projections in the mouse brain after transplantation

Publisher

London: Nature Publishing Group UK

Journal title

Molecular psychiatry, 2021-07, Vol.26 (7), p.2964-2976

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Numerous studies have used human pluripotent stem cell-derived cerebral organoids to elucidate the mystery of human brain development and model neurological diseases in vitro, but the potential for grafted organoid-based therapy in vivo remains unknown. Here, we optimized a culturing protocol capable of efficiently generating small human cerebral o...

Alternative Titles

Full title

Human cerebral organoids establish subcortical projections in the mouse brain after transplantation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8505255

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8505255

Other Identifiers

ISSN

1359-4184

E-ISSN

1476-5578

DOI

10.1038/s41380-020-00910-4

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