Genetic contributions to alcohol use disorder treatment outcomes: a genome-wide pharmacogenomics stu...
Genetic contributions to alcohol use disorder treatment outcomes: a genome-wide pharmacogenomics study
About this item
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Author / Creator
Biernacka, Joanna M , Coombes, Brandon J , Batzler, Anthony , Ho, Ada Man-Choi , Geske, Jennifer R , Frank, Josef , Hodgkinson, Colin , Skime, Michelle , Colby, Colin , Zillich, Lea , Pozsonyiova, Sofia , Ho, Ming-Fen , Kiefer, Falk , Rietschel, Marcella , Weinshilboum, Richard , O'Malley, Stephanie S , Mann, Karl , Anton, Ray , Goldman, David and Karpyak, Victor M
Publisher
England: Nature Publishing Group
Journal title
Language
English
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Publisher
England: Nature Publishing Group
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Scope and Contents
Contents
Naltrexone can aid in reducing alcohol consumption, while acamprosate supports abstinence; however, not all patients with alcohol use disorder (AUD) benefit from these treatments. Here we present the first genome-wide association study of AUD treatment outcomes based on data from the COMBINE and PREDICT studies of acamprosate and naltrexone, and th...
Alternative Titles
Full title
Genetic contributions to alcohol use disorder treatment outcomes: a genome-wide pharmacogenomics study
Authors, Artists and Contributors
Author / Creator
Coombes, Brandon J
Batzler, Anthony
Ho, Ada Man-Choi
Geske, Jennifer R
Frank, Josef
Hodgkinson, Colin
Skime, Michelle
Colby, Colin
Zillich, Lea
Pozsonyiova, Sofia
Ho, Ming-Fen
Kiefer, Falk
Rietschel, Marcella
Weinshilboum, Richard
O'Malley, Stephanie S
Mann, Karl
Anton, Ray
Goldman, David
Karpyak, Victor M
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8505452
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8505452
Other Identifiers
ISSN
0893-133X,1740-634X
E-ISSN
1740-634X
DOI
10.1038/s41386-021-01097-0