Shear-mediated platelet activation in the free flow II: Evolving mechanobiological mechanisms reveal...
Shear-mediated platelet activation in the free flow II: Evolving mechanobiological mechanisms reveal an identifiable signature of activation and a bi-directional platelet dyscrasia with thrombotic and bleeding features
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Publisher
Kidlington: Elsevier Ltd
Journal title
Language
English
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Publisher
Kidlington: Elsevier Ltd
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Scope and Contents
Contents
Shear-mediated platelet activation (SMPA) in the “free flow” is the net result of a range of cell mechanobiological mechanisms. Previously, we outlined three main groups of mechanisms including: 1) mechano-destruction - i.e. additive platelet (membrane) damage; 2) mechano-activation - i.e. activation of shear-sensitive ion channels and pores; and 3...
Alternative Titles
Full title
Shear-mediated platelet activation in the free flow II: Evolving mechanobiological mechanisms reveal an identifiable signature of activation and a bi-directional platelet dyscrasia with thrombotic and bleeding features
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8513575
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8513575
Other Identifiers
ISSN
0021-9290
E-ISSN
1873-2380
DOI
10.1016/j.jbiomech.2021.110415
