Early treatment of COVID-19 with anakinra guided by soluble urokinase plasminogen receptor plasma le...
Early treatment of COVID-19 with anakinra guided by soluble urokinase plasminogen receptor plasma levels: a double-blind, randomized controlled phase 3 trial
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Author / Creator
Kyriazopoulou, Evdoxia , Poulakou, Garyfallia , Milionis, Haralampos , Metallidis, Simeon , Adamis, Georgios , Tsiakos, Konstantinos , Fragkou, Archontoula , Rapti, Aggeliki , Damoulari, Christina , Fantoni, Massimo , Kalomenidis, Ioannis , Chrysos, Georgios , Angheben, Andrea , Kainis, Ilias , Alexiou, Zoi , Castelli, Francesco , Serino, Francesco Saverio , Tsilika, Maria , Bakakos, Petros , Nicastri, Emanuele , Tzavara, Vassiliki , Kostis, Evangelos , Dagna, Lorenzo , Koufargyris, Panagiotis , Dimakou, Katerina , Savvanis, Spyridon , Tzatzagou, Glykeria , Chini, Maria , Cavalli, Giulio , Bassetti, Matteo , Katrini, Konstantina , Kotsis, Vasileios , Tsoukalas, George , Selmi, Carlo , Bliziotis, Ioannis , Samarkos, Michael , Doumas, Michael , Ktena, Sofia , Masgala, Aikaterini , Papanikolaou, Ilias , Kosmidou, Maria , Myrodia, Dimitra-Melia , Argyraki, Aikaterini , Cardellino, Chiara Simona , Koliakou, Katerina , Katsigianni, Eleni-Ioanna , Rapti, Vassiliki , Giannitsioti, Efthymia , Cingolani, Antonella , Micha, Styliani , Akinosoglou, Karolina , Liatsis-Douvitsas, Orestis , Symbardi, Styliani , Gatselis, Nikolaos , Mouktaroudi, Maria , Ippolito, Giuseppe , Florou, Eleni , Kotsaki, Antigone , Netea, Mihai G. , Eugen-Olsen, Jesper , Kyprianou, Miltiades , Panagopoulos, Periklis , Dalekos, George N. and Giamarellos-Bourboulis, Evangelos J.
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Early increase of soluble urokinase plasminogen activator receptor (suPAR) serum levels is indicative of increased risk of progression of coronavirus disease 2019 (COVID-19) to respiratory failure. The SAVE-MORE double-blind, randomized controlled trial evaluated the efficacy and safety of anakinra, an IL-1α/β inhibitor, in 594 patients with COVID-...
Alternative Titles
Full title
Early treatment of COVID-19 with anakinra guided by soluble urokinase plasminogen receptor plasma levels: a double-blind, randomized controlled phase 3 trial
Authors, Artists and Contributors
Author / Creator
Poulakou, Garyfallia
Milionis, Haralampos
Metallidis, Simeon
Adamis, Georgios
Tsiakos, Konstantinos
Fragkou, Archontoula
Rapti, Aggeliki
Damoulari, Christina
Fantoni, Massimo
Kalomenidis, Ioannis
Chrysos, Georgios
Angheben, Andrea
Kainis, Ilias
Alexiou, Zoi
Castelli, Francesco
Serino, Francesco Saverio
Tsilika, Maria
Bakakos, Petros
Nicastri, Emanuele
Tzavara, Vassiliki
Kostis, Evangelos
Dagna, Lorenzo
Koufargyris, Panagiotis
Dimakou, Katerina
Savvanis, Spyridon
Tzatzagou, Glykeria
Chini, Maria
Cavalli, Giulio
Bassetti, Matteo
Katrini, Konstantina
Kotsis, Vasileios
Tsoukalas, George
Selmi, Carlo
Bliziotis, Ioannis
Samarkos, Michael
Doumas, Michael
Ktena, Sofia
Masgala, Aikaterini
Papanikolaou, Ilias
Kosmidou, Maria
Myrodia, Dimitra-Melia
Argyraki, Aikaterini
Cardellino, Chiara Simona
Koliakou, Katerina
Katsigianni, Eleni-Ioanna
Rapti, Vassiliki
Giannitsioti, Efthymia
Cingolani, Antonella
Micha, Styliani
Akinosoglou, Karolina
Liatsis-Douvitsas, Orestis
Symbardi, Styliani
Gatselis, Nikolaos
Mouktaroudi, Maria
Ippolito, Giuseppe
Florou, Eleni
Kotsaki, Antigone
Netea, Mihai G.
Eugen-Olsen, Jesper
Kyprianou, Miltiades
Panagopoulos, Periklis
Dalekos, George N.
Giamarellos-Bourboulis, Evangelos J.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8516650
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8516650
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/s41591-021-01499-z
