NDRG1 enhances the sensitivity of cetuximab by modulating EGFR trafficking in colorectal cancer
NDRG1 enhances the sensitivity of cetuximab by modulating EGFR trafficking in colorectal cancer
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
N-myc downstream-regulated gene 1 (NDRG1) is a key regulator that interacts with many classic tumor signaling pathways, including some molecules downstream of the epidermal growth factor receptor (EGFR). However, whether NDRG1 is involved in the mechanism of resistance to cetuximab (CTX), the first monoclonal antibody targeting the EGFR has not bee...
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Full title
NDRG1 enhances the sensitivity of cetuximab by modulating EGFR trafficking in colorectal cancer
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8516652
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8516652
Other Identifiers
ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/s41388-021-01962-8
