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A genetically encoded sensor for measuring serotonin dynamics

A genetically encoded sensor for measuring serotonin dynamics

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8544647

A genetically encoded sensor for measuring serotonin dynamics

About this item

Full title

A genetically encoded sensor for measuring serotonin dynamics

Publisher

New York: Nature Publishing Group US

Journal title

Nature neuroscience, 2021-05, Vol.24 (5), p.746-752

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Serotonin (5-HT) is a phylogenetically conserved monoamine neurotransmitter modulating important processes in the brain. To directly visualize the release of 5-HT, we developed a genetically encoded G-protein-coupled receptor (GPCR)-activation-based 5-HT (GRAB
5-HT
) sensor with high sensitivity, high selectivity, subsecond kinetics and subce...

Alternative Titles

Full title

A genetically encoded sensor for measuring serotonin dynamics

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8544647

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8544647

Other Identifiers

ISSN

1097-6256

E-ISSN

1546-1726

DOI

10.1038/s41593-021-00823-7

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