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Trained innate immunity, long-lasting epigenetic modulation, and skewed myelopoiesis by heme

Trained innate immunity, long-lasting epigenetic modulation, and skewed myelopoiesis by heme

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8545490

Trained innate immunity, long-lasting epigenetic modulation, and skewed myelopoiesis by heme

About this item

Full title

Trained innate immunity, long-lasting epigenetic modulation, and skewed myelopoiesis by heme

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2021-10, Vol.118 (42), p.1-10

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Trained immunity defines long-lasting adaptations of innate immunity based on transcriptional and epigenetic modifications of myeloid cells and their bone marrow progenitors [M. Divangahi et al., Nat. Immunol. 22, 2–6 (2021)]. Innate immune cells, however, do not exclusively differentiate between foreign and self but also react to host-derived mole...

Alternative Titles

Full title

Trained innate immunity, long-lasting epigenetic modulation, and skewed myelopoiesis by heme

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8545490

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8545490

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.2102698118

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