Potential of polygenic risk scores for improving population estimates of women’s breast cancer genet...
Potential of polygenic risk scores for improving population estimates of women’s breast cancer genetic risks
About this item
Full title
Author / Creator
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Purpose
Breast cancer risk has conventionally been assessed using family history (FH) and rare high/moderate penetrance pathogenic variants (PVs), notably in
BRCA1/2
, and more recently
PALB2
,
CHEK2
, and
ATM
. In addition to these PVs, it is now possible to use increasingly predictive polygenic risk scores (PRS) as well...
Alternative Titles
Full title
Potential of polygenic risk scores for improving population estimates of women’s breast cancer genetic risks
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8553614
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8553614
Other Identifiers
ISSN
1098-3600
E-ISSN
1530-0366
DOI
10.1038/s41436-021-01258-y
