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The transcription factor PBX3 promotes tumor cell growth through transcriptional suppression of the...

The transcription factor PBX3 promotes tumor cell growth through transcriptional suppression of the...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8564524

The transcription factor PBX3 promotes tumor cell growth through transcriptional suppression of the tumor suppressor p53

About this item

Full title

The transcription factor PBX3 promotes tumor cell growth through transcriptional suppression of the tumor suppressor p53

Publisher

Singapore: Springer Singapore

Journal title

Acta pharmacologica Sinica, 2021-11, Vol.42 (11), p.1888-1899

Language

English

Formats

Publication information

Publisher

Singapore: Springer Singapore

More information

Scope and Contents

Contents

Pre-B-cell leukemia transcription factor 3 (PBX3) is a member of the PBX family and contains a highly conserved homologous domain. PBX3 is involved in the progression of gastric cancer, colorectal cancer, and prostate cancer; however, the detailed mechanism by which it promotes tumor growth remains to be elucidated. Here, we found that
PBX3
s...

Alternative Titles

Full title

The transcription factor PBX3 promotes tumor cell growth through transcriptional suppression of the tumor suppressor p53

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8564524

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8564524

Other Identifiers

ISSN

1671-4083

E-ISSN

1745-7254

DOI

10.1038/s41401-020-00599-9

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