A wake-up call for cancer DNA damage: the role of Schlafen 11 (SLFN11) across multiple cancers
A wake-up call for cancer DNA damage: the role of Schlafen 11 (SLFN11) across multiple cancers
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
DNA-damaging agents exploit increased genomic instability, a hallmark of cancer. Recently, inhibitors targeting the DNA damage response (DDR) pathways, such as PARP inhibitors, have also shown promising therapeutic potential. However, not all tumors respond well to these treatments, suggesting additional determinants of response are required. Schla...
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Full title
A wake-up call for cancer DNA damage: the role of Schlafen 11 (SLFN11) across multiple cancers
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8576031
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8576031
Other Identifiers
ISSN
0007-0920
E-ISSN
1532-1827
DOI
10.1038/s41416-021-01476-w
