CST6 protein and peptides inhibit breast cancer bone metastasis by suppressing CTSB activity and ost...
CST6 protein and peptides inhibit breast cancer bone metastasis by suppressing CTSB activity and osteoclastogenesis
About this item
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Author / Creator
Li, Xiaoxun , Liang, Yajun , Lian, Cheng , Peng, Fangli , Xiao, Yansen , He, Yunfei , Ma, Chengxin , Wang, Yuan , Zhang, Peiyuan , Deng, Yuhan , Su, Yunpeng , Luo, Cheng , Kong, Xiangyin , Yang, Qingcheng , Liu, Tong and Hu, Guohong
Publisher
Australia: Ivyspring International Publisher Pty Ltd
Journal title
Language
English
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Publication information
Publisher
Australia: Ivyspring International Publisher Pty Ltd
Subjects
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Scope and Contents
Contents
Bone metastasis is a frequent symptom of breast cancer and current targeted therapy has limited efficacy. Osteoclasts play critical roles to drive osteolysis and metastatic outgrowth of tumor cells in bone. Previously we identified CST6 as a secretory protein significantly downregulated in bone-metastatic breast cancer cells. Functional analysis sh...
Alternative Titles
Full title
CST6 protein and peptides inhibit breast cancer bone metastasis by suppressing CTSB activity and osteoclastogenesis
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8581426
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8581426
Other Identifiers
ISSN
1838-7640
E-ISSN
1838-7640
DOI
10.7150/thno.62187
