Regulation of a progenitor gene program by SOX4 is essential for mammary tumor proliferation
Regulation of a progenitor gene program by SOX4 is essential for mammary tumor proliferation
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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In breast cancer the transcription factor SOX4 has been shown to be associated with poor survival, increased tumor size and metastasis formation. This has mostly been attributed to the ability of SOX4 to regulate Epithelial-to-Mesenchymal-Transition (EMT). However, SOX4 regulates target gene transcription in a context-dependent manner that is deter...
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Full title
Regulation of a progenitor gene program by SOX4 is essential for mammary tumor proliferation
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8585668
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8585668
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ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/s41388-021-02004-z
