Brain structural abnormalities in obesity: relation to age, genetic risk, and common psychiatric dis...
Brain structural abnormalities in obesity: relation to age, genetic risk, and common psychiatric disorders: Evidence through univariate and multivariate mega-analysis including 6420 participants from the ENIGMA MDD working group
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Author / Creator
Opel, Nils , Thalamuthu, Anbupalam , Milaneschi, Yuri , Grotegerd, Dominik , Flint, Claas , Leenings, Ramona , Goltermann, Janik , Richter, Maike , Hahn, Tim , Woditsch, Georg , Berger, Klaus , Hermesdorf, Marco , McIntosh, Andrew , Whalley, Heather C. , Harris, Mathew A. , MacMaster, Frank P. , Walter, Henrik , Veer, Ilya M. , Frodl, Thomas , Carballedo, Angela , Krug, Axel , Nenadic, Igor , Kircher, Tilo , Aleman, Andre , Groenewold, Nynke A. , Stein, Dan J. , Soares, Jair C. , Zunta-Soares, Giovana B. , Mwangi, Benson , Wu, Mon-Ju , Walter, Martin , Li, Meng , Harrison, Ben J. , Davey, Christopher G. , Cullen, Kathryn R. , Klimes-Dougan, Bonnie , Mueller, Bryon A. , Sämann, Philipp G. , Penninx, Brenda , Nawijn, Laura , Veltman, Dick J. , Aftanas, Lyubomir , Brak, Ivan V. , Filimonova, Elena A. , Osipov, Evgeniy A. , Reneman, Liesbeth , Schrantee, Anouk , Grabe, Hans J. , Van der Auwera, Sandra , Wittfeld, Katharina , Hosten, Norbert , Völzke, Henry , Sim, Kang , Gotlib, Ian H. , Sacchet, Matthew D. , Lagopoulos, Jim , Hatton, Sean N. , Hickie, Ian , Pozzi, Elena , Thompson, Paul M. , Jahanshad, Neda , Schmaal, Lianne , Baune, Bernhard T. and Dannlowski, Udo
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Emerging evidence suggests that obesity impacts brain physiology at multiple levels. Here we aimed to clarify the relationship between obesity and brain structure using structural MRI (
n
= 6420) and genetic data (
n
= 3907) from the ENIGMA Major Depressive Disorder (MDD) working group. Obesity (BMI > 30) was significantly associated...
Alternative Titles
Full title
Brain structural abnormalities in obesity: relation to age, genetic risk, and common psychiatric disorders: Evidence through univariate and multivariate mega-analysis including 6420 participants from the ENIGMA MDD working group
Authors, Artists and Contributors
Author / Creator
Thalamuthu, Anbupalam
Milaneschi, Yuri
Grotegerd, Dominik
Flint, Claas
Leenings, Ramona
Goltermann, Janik
Richter, Maike
Hahn, Tim
Woditsch, Georg
Berger, Klaus
Hermesdorf, Marco
McIntosh, Andrew
Whalley, Heather C.
Harris, Mathew A.
MacMaster, Frank P.
Walter, Henrik
Veer, Ilya M.
Frodl, Thomas
Carballedo, Angela
Krug, Axel
Nenadic, Igor
Kircher, Tilo
Aleman, Andre
Groenewold, Nynke A.
Stein, Dan J.
Soares, Jair C.
Zunta-Soares, Giovana B.
Mwangi, Benson
Wu, Mon-Ju
Walter, Martin
Li, Meng
Harrison, Ben J.
Davey, Christopher G.
Cullen, Kathryn R.
Klimes-Dougan, Bonnie
Mueller, Bryon A.
Sämann, Philipp G.
Penninx, Brenda
Nawijn, Laura
Veltman, Dick J.
Aftanas, Lyubomir
Brak, Ivan V.
Filimonova, Elena A.
Osipov, Evgeniy A.
Reneman, Liesbeth
Schrantee, Anouk
Grabe, Hans J.
Van der Auwera, Sandra
Wittfeld, Katharina
Hosten, Norbert
Völzke, Henry
Sim, Kang
Gotlib, Ian H.
Sacchet, Matthew D.
Lagopoulos, Jim
Hatton, Sean N.
Hickie, Ian
Pozzi, Elena
Thompson, Paul M.
Jahanshad, Neda
Schmaal, Lianne
Baune, Bernhard T.
Dannlowski, Udo
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8589644
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8589644
Other Identifiers
ISSN
1359-4184
E-ISSN
1476-5578
DOI
10.1038/s41380-020-0774-9
