Log in to save to my catalogue

Comprehensive molecular profiling of UV-induced metastatic melanoma in Nme1/Nme2-deficient mice reve...

Comprehensive molecular profiling of UV-induced metastatic melanoma in Nme1/Nme2-deficient mice reve...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8595820

Comprehensive molecular profiling of UV-induced metastatic melanoma in Nme1/Nme2-deficient mice reveals novel markers of survival in human patients

About this item

Full title

Comprehensive molecular profiling of UV-induced metastatic melanoma in Nme1/Nme2-deficient mice reveals novel markers of survival in human patients

Publisher

London: Nature Publishing Group UK

Journal title

Oncogene, 2021-11, Vol.40 (45), p.6329-6342

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Hepatocyte growth factor-overexpressing mice that harbor a deletion of the
Ink4a
/
p16
locus (HP mice) form melanomas with low metastatic potential in response to UV irradiation. Here we report that these tumors become highly metastatic following hemizygous deletion of the
Nme1
and
Nme2
metastasis suppressor genes (HPN mice)...

Alternative Titles

Full title

Comprehensive molecular profiling of UV-induced metastatic melanoma in Nme1/Nme2-deficient mice reveals novel markers of survival in human patients

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8595820

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8595820

Other Identifiers

ISSN

0950-9232

E-ISSN

1476-5594

DOI

10.1038/s41388-021-01998-w

How to access this item