Comprehensive molecular profiling of UV-induced metastatic melanoma in Nme1/Nme2-deficient mice reve...
Comprehensive molecular profiling of UV-induced metastatic melanoma in Nme1/Nme2-deficient mice reveals novel markers of survival in human patients
About this item
Full title
Author / Creator
Leonard, M. Kathryn , Puts, Gemma S. , Pamidimukkala, Nidhi , Adhikary, Gautam , Xu, Yili , Kwok, Eric , Jin, Yuxin , Snyder, Devin , Matsangos, Nicolette , Novak, Marián , Mahurkar, Anup , Shetty, Amol C. , Slominski, Radomir M. , De Fabo, Edward C. , Noonan, Frances P. , Day, Chi-Ping , Rigi, Mohammed , Slominski, Andrzej T. , Webb, Michelle G. , Craig, David W. , Merlino, Glenn , Eckert, Richard L. , Carpten, John D. , Manojlovic, Zarko and Kaetzel, David M.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Hepatocyte growth factor-overexpressing mice that harbor a deletion of the
Ink4a
/
p16
locus (HP mice) form melanomas with low metastatic potential in response to UV irradiation. Here we report that these tumors become highly metastatic following hemizygous deletion of the
Nme1
and
Nme2
metastasis suppressor genes (HPN mice)...
Alternative Titles
Full title
Comprehensive molecular profiling of UV-induced metastatic melanoma in Nme1/Nme2-deficient mice reveals novel markers of survival in human patients
Authors, Artists and Contributors
Author / Creator
Puts, Gemma S.
Pamidimukkala, Nidhi
Adhikary, Gautam
Xu, Yili
Kwok, Eric
Jin, Yuxin
Snyder, Devin
Matsangos, Nicolette
Novak, Marián
Mahurkar, Anup
Shetty, Amol C.
Slominski, Radomir M.
De Fabo, Edward C.
Noonan, Frances P.
Day, Chi-Ping
Rigi, Mohammed
Slominski, Andrzej T.
Webb, Michelle G.
Craig, David W.
Merlino, Glenn
Eckert, Richard L.
Carpten, John D.
Manojlovic, Zarko
Kaetzel, David M.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8595820
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8595820
Other Identifiers
ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/s41388-021-01998-w