Lidocaine Alleviates Sepsis-Induced Acute Lung Injury in Mice by Suppressing Tissue Factor and Matri...
Lidocaine Alleviates Sepsis-Induced Acute Lung Injury in Mice by Suppressing Tissue Factor and Matrix Metalloproteinase-2/9
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Author / Creator
Zheng, Binbin , Yang, Hongbo , Zhang, Jianan , Wang, Xueli , Sun, Hao , Hu, Fan , Li, Qian , Jiang, Liping , Su, Yue , Peng, Qilin , Tang, Yulin , Liu, Wen-Tao , He, Xueming , Fan, Yixin and Zhu, Xia
Publisher
United States: Hindawi
Journal title
Language
English
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Publication information
Publisher
United States: Hindawi
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Scope and Contents
Contents
Acute lung injury (ALI) is one of the fatal symptoms of sepsis. However, there were no effective clinical treatments. TF accumulation-induced fibrin deposit formations and coagulation abnormalities in pulmonary vessels contribute to the lethality of ALI. Suppressor of cytokine signaling 3 (SOCS3) acts as an endogenous negative regulator of the TLR4...
Alternative Titles
Full title
Lidocaine Alleviates Sepsis-Induced Acute Lung Injury in Mice by Suppressing Tissue Factor and Matrix Metalloproteinase-2/9
Authors, Artists and Contributors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8604580
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8604580
Other Identifiers
ISSN
1942-0900
E-ISSN
1942-0994
DOI
10.1155/2021/3827501
