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A proteome-wide map of 20(S)-hydroxycholesterol interactors in cell membranes

A proteome-wide map of 20(S)-hydroxycholesterol interactors in cell membranes

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8607797

A proteome-wide map of 20(S)-hydroxycholesterol interactors in cell membranes

About this item

Full title

A proteome-wide map of 20(S)-hydroxycholesterol interactors in cell membranes

Publisher

New York: Nature Publishing Group US

Journal title

Nature chemical biology, 2021-12, Vol.17 (12), p.1271-1280

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Oxysterols (OHCs) are hydroxylated cholesterol metabolites that play ubiquitous roles in health and disease. Due to the non-covalent nature of their interactions and their unique partitioning in membranes, the analysis of live-cell, proteome-wide interactions of OHCs remains an unmet challenge. Here, we present a structurally precise chemoproteomic...

Alternative Titles

Full title

A proteome-wide map of 20(S)-hydroxycholesterol interactors in cell membranes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8607797

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8607797

Other Identifiers

ISSN

1552-4450

E-ISSN

1552-4469

DOI

10.1038/s41589-021-00907-2

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