A proteome-wide map of 20(S)-hydroxycholesterol interactors in cell membranes
A proteome-wide map of 20(S)-hydroxycholesterol interactors in cell membranes
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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Oxysterols (OHCs) are hydroxylated cholesterol metabolites that play ubiquitous roles in health and disease. Due to the non-covalent nature of their interactions and their unique partitioning in membranes, the analysis of live-cell, proteome-wide interactions of OHCs remains an unmet challenge. Here, we present a structurally precise chemoproteomic...
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A proteome-wide map of 20(S)-hydroxycholesterol interactors in cell membranes
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8607797
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8607797
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ISSN
1552-4450
E-ISSN
1552-4469
DOI
10.1038/s41589-021-00907-2