Bacterial lectin BambL acts as a B cell superantigen
Bacterial lectin BambL acts as a B cell superantigen
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Publisher
Cham: Springer International Publishing
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Language
English
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Publisher
Cham: Springer International Publishing
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Contents
B cell superantigens crosslink conserved domains of B cell receptors (BCRs) and cause dysregulated, polyclonal B cell activation irrespective of normal BCR-antigen complementarity. The cells typically succumb to activation-induced cell death, which can impede the adaptive immune response and favor infection. In the present study, we demonstrate tha...
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Full title
Bacterial lectin BambL acts as a B cell superantigen
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8629787
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8629787
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ISSN
1420-682X
E-ISSN
1420-9071
DOI
10.1007/s00018-021-04009-z