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Bacterial lectin BambL acts as a B cell superantigen

Bacterial lectin BambL acts as a B cell superantigen

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8629787

Bacterial lectin BambL acts as a B cell superantigen

About this item

Full title

Bacterial lectin BambL acts as a B cell superantigen

Publisher

Cham: Springer International Publishing

Journal title

Cellular and molecular life sciences : CMLS, 2021-12, Vol.78 (24), p.8165-8186

Language

English

Formats

Publication information

Publisher

Cham: Springer International Publishing

More information

Scope and Contents

Contents

B cell superantigens crosslink conserved domains of B cell receptors (BCRs) and cause dysregulated, polyclonal B cell activation irrespective of normal BCR-antigen complementarity. The cells typically succumb to activation-induced cell death, which can impede the adaptive immune response and favor infection. In the present study, we demonstrate tha...

Alternative Titles

Full title

Bacterial lectin BambL acts as a B cell superantigen

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8629787

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8629787

Other Identifiers

ISSN

1420-682X

E-ISSN

1420-9071

DOI

10.1007/s00018-021-04009-z

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