Trivalent nucleoside-modified mRNA vaccine yields durable memory B cell protection against genital h...
Trivalent nucleoside-modified mRNA vaccine yields durable memory B cell protection against genital herpes in preclinical models
About this item
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Author / Creator
Awasthi, Sita , Knox, James J. , Desmond, Angela , Alameh, Mohamad-Gabriel , Gaudette, Brian T. , Lubinski, John M. , Naughton, Alexis , Hook, Lauren M. , Egan, Kevin P. , Tam, Ying K. , Pardi, Norbert , Allman, David , Luning Prak, Eline T. , Cancro, Michael P. , Weissman, Drew , Cohen, Gary H. and Friedman, Harvey M.
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
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Publication information
Publisher
United States: American Society for Clinical Investigation
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Scope and Contents
Contents
Nucleoside-modified mRNA vaccines have gained global attention because of COVID-19. We evaluated a similar vaccine approach for preventing a chronic, latent genital infection rather than an acute respiratory infection. We used animal models to compare an HSV-2 trivalent nucleoside-modified mRNA vaccine with the same antigens prepared as proteins, w...
Alternative Titles
Full title
Trivalent nucleoside-modified mRNA vaccine yields durable memory B cell protection against genital herpes in preclinical models
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8631595
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8631595
Other Identifiers
ISSN
1558-8238,0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI152310
