STAT3 activation in large granular lymphocyte leukemia is associated with cytokine signaling and DNA...
STAT3 activation in large granular lymphocyte leukemia is associated with cytokine signaling and DNA hypermethylation
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Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Large granular lymphocyte leukemia (LGLL) is characterized by somatic gain-of-function
STAT3
mutations. However, the functional effects of
STAT3
mutations on primary LGLL cells have not been studied in detail. In this study, we show that CD8+ T cells isolated from
STAT3
mutated LGLL patients have high protein levels of epigenetic...
Alternative Titles
Full title
STAT3 activation in large granular lymphocyte leukemia is associated with cytokine signaling and DNA hypermethylation
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8632689
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8632689
Other Identifiers
ISSN
0887-6924,1476-5551
E-ISSN
1476-5551
DOI
10.1038/s41375-021-01296-0
