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Randomised clinical trials in critical care: past, present and future

Randomised clinical trials in critical care: past, present and future

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8636283

Randomised clinical trials in critical care: past, present and future

About this item

Full title

Randomised clinical trials in critical care: past, present and future

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Intensive care medicine, 2022-02, Vol.48 (2), p.164-178

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Randomised clinical trials (RCTs) are the gold standard for providing unbiased evidence of intervention effects. Here, we provide an overview of the history of RCTs and discuss the major challenges and limitations of current critical care RCTs, including overly optimistic effect sizes; unnuanced conclusions based on dichotomization of results; limi...

Alternative Titles

Full title

Randomised clinical trials in critical care: past, present and future

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8636283

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8636283

Other Identifiers

ISSN

0342-4642

E-ISSN

1432-1238

DOI

10.1007/s00134-021-06587-9

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