Catalytic asymmetric addition of an amine N–H bond across internal alkenes
Catalytic asymmetric addition of an amine N–H bond across internal alkenes
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
Hydroamination of alkenes, the addition of the N–H bond of an amine across an alkene, is a fundamental, yet challenging, organic transformation that creates an alkylamine from two abundant chemical feedstocks, alkenes and amines, with full atom economy
1
–
3
. The reaction is particularly important because amines, especially chiral amin...
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Full title
Catalytic asymmetric addition of an amine N–H bond across internal alkenes
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8638802
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8638802
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-020-2919-z
